In the time after their sin and expulsion from the Garden Adam and Eve must have felt incredible despair. They had experienced life both before and after the curse, the only ones to do so, and had first hand knowledge of the difference. And what a difference it was. Even the part of it we can relate to had to have been devastating.
For example suppose that
one day you were the resident manager of the world’s richest and most luxurious
estate, with all of its comforts and privileges, and the next you were a poor
hardscrabble farmer, at the opposite end of the economic and social structure.
And that was just the beginning. How about no longer being immortal, no longer
one with your Creator in spirit.